Meet our doctoral candidate Luigi Dragonetti
Meet our doctoral candidate: Luigi Dragonetti from Italy 🇮🇹
He will work on developing a sample-to-answer biosensor based on the electrode switchable DNA based nanolever at Dublic City University (Ireland 🇮🇪) under the supervision of Professor Robert Forster.
He recently obtained his Master Degree at the University of Bologna (Italy 🇮🇹) with a thesis focusing on the production and characterization of metal thin films, developing operational skills in SECM and XPS techniques.
If you want to know more, click the button below and read his full bio and the description of his doctoral project in the dedicated section.
New paper in Electrochimica Acta
Electrocatalytic amplification of coreactant electrochemiluminescence using redox mediators
Sara Knežević, Emily Kerr, Giovanni Valenti, Francesco Paolucci, Paul S. Francis, Conor F. Hogan, Neso Sojic, Frédéric Kanoufi
Published in Electrochimica Acta
Electrochemiluminescence (ECL) has emerged as a sensitive analytical technique with a wide range of applications. While recent studies have begun to explore the role of redox mediators to facilitate ECL systems, this work extends these foundational insights by developing a comprehensive theoretical framework that supports, generalizes, and rationalizes mechanistic pathways borrowed from molecular electrocatalysis. This advancement is demonstrated through the electrocatalytic amplification of coreactant ECL within the [Ru(bpy)3]2+/TPrA system, utilizing a water-soluble redox-active Ir(III) complex as an electrocatalyst. Our investigation unveils previously uncharted mechanisms that enable the enhancement of Ru complex ECL at low electrode potentials, crucially without requiring the direct oxidation of [Ru(bpy)3]2+ or TPrA at the electrode, thus offering a deeper understanding of ECL activation through moelcular electrocatalysis. Through an integrated approach combining electrochemical analysis, spectroscopic investigation, and finite element modeling, we elucidate how the redox mediator critically modulates ECL efficiency by controlling the kinetics of radical species production and decay. The mediation by the Ir(III) complex not only governs the generation of TPrA radicals and excited [Ru(bpy)3]2+ states, thereby enhancing ECL intensity, but also the conditions under which ECL can be quenched. Further exploration of the mediator’s redox characteristics provides predictive insights into ECL behavior, underscoring the mediator’s redox potential as pivotal in determining ECL onset, peak potential, and intensity. This refined understanding paves the way for tailoring ECL systems for enhanced performance in analytical, imaging, and biomedical applications through the judicious selection of redox mediators.
Graphical abstract
Meet our doctoral candidate Elisa D'Arrigo
Meet our doctoral candidate: Elisa D’Arrigo from Italy 🇮🇹
Elisa D’Arrigo will work on ECL from small cells at University of Bordeaux (France 🇫🇷) under the supervision of Professor Neso Sojic.
Over the last year, she was employed as a research fellow in the laboratory of Cellular Chemistry and Functional Imaging at the Department of Chemistry “G. Ciamician” of Alma Mater Studiorum University of Bologna
If you want to know more, click the button below and read her full bio and the description of her doctoral project in the dedicated section.
Meet our doctoral candidate Nayla Takeuti
Meet our doctoral candidate: Nayla Takeuti from Brazil 🇧🇷
Nayla Takeuti will work on earth abundant metal and free metal water soluble compounds for ECL at University of Milan (Italy 🇮🇹) under the supervision of Professor Luisa De Cola.
She recently obtained her Master Degree at the University of São Paulo (Brazil) with a thesis on The Development of Platforms for Detection of Tuberculosis Biomarkers.
If you want to know more, click the button below and read her full bio and the description of her doctoral project in the dedicated section.
Call for applications: 1 PhD position available
Join our electrochemiluminescence doctoral network for early sepsis diagnosis:
1 PhD position still open under the supervision of Dr. Elena Benito-Peña
Home institution: Universidad Complutense de Madrid (Spain)
Project Title: Selection and production of recombinant antibodies (rAb) for biosensing applications
Application deadline: September 27, 2024
For more info & to apply: https://euraxess.ec.europa.eu/jobs/270616
Meet our doctoral candidate Chiara Giustini
Meet our doctoral candidate: Chiara Giustini from Italy 🇮🇹
Chiara Giustini will work on ECL-active dye doped C-dots at CIC BiomaGUNE (Spain 🇪🇸) under the supervision of Professor Maurizio Prato.
She recently obtained her Master Degree in Chemistry at the University of Palermo (Italy), discussing an experimental thesis entitled “Graphene oxide-based materials for white light sources”.
If you want to know more, click the button below and read her full bio and the description of her doctoral project in the dedicated section.