Overcoming kinetic barriers of remote electrochemiluminescence on boron-doped diamond via catalytic coreactant oxidation
Alessandro Fracassa, Chiara Mariani, Andrea Fiorani, Yasuaki Einaga, Conor F. Hogan, Francesco Paolucci, Neso Sojic, Paul S. Francis and Giovanni Valenti
Published in Chemical Communications
Abstract
The effectiveness of boron-doped diamond (BDD) as a platform for electrochemiluminescence (ECL) bead-based bioassays is hindered by the sluggish rate of heterogeneous tri-n-propylamine (TPrA) oxidation. To address this, we investigate the ECL of Ru(II)-coated microbeads in the presence of a redox mediator, exploring the effect of applied potential and electrode surface terminations. Using a redox mediator, the ECL signal on BDD is enhanced by up to 46-fold.
